A NOVEL APPROACH TO TERMINATE ROOF-DEPENDENT ATRIAL FLUTTER WITH EPICARDIAL CONDUCTION THROUGH SEPTOPULMONARY BUNDLE

A novel approach to terminate roof-dependent atrial flutter with epicardial conduction through septopulmonary bundle

Abstract Atrial flutter, a prevalent cardiac arrhythmia, is primarily characterized by reentrant circuits in the right atrium.However, atypical forms of atrial flutter present distinct challenges in terms of diagnosis and treatment.In this study, we examine three noteworthy clinical cases of atypical atrial flutter, which offer compelling evidence

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Identification of Olfactory Receptors Responding to Androstenone and the Key Structure Determinant in Domestic Pig

Olfactory receptors (ORs) are members of the transmembrane G protein-coupled receptor superfamily, playing a crucial role in odor recognition, which further mediates crucial biological processes in mammals.In sows, androstenone can trigger sexual behaviors through olfaction, but the underlying mechanism remains to be explored.To efficiently and acc

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Intrathecal administration of a novel siRNA modality extends survival and improves motor function in the SOD1G93A ALS mouse model

Antisense oligonucleotides (ASOs) were the first modality to pioneer targeted gene knockdown in the treatment of amyotrophic lateral sclerosis (ALS) caused by mutant superoxide dismutase 1 (SOD1).RNA interference (RNAi) is another mechanism of gene Decorations silencing in which short interfering RNAs (siRNAs) effectively degrade complementary tran

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